Exosomes Stem Cell Therapy

Stem Cell Therapy

There are different kinds of cells that are collectively referred to as “stem cells” including embryonic stem cells, non-embryonic or adult stem cells, induced pluripotent stem cells, and cord blood cells. The stem cells are distinguished by their ability to regenerate other types of cells, which is an attribute that no other cell in the body has. Embryonic stem cells are the most basic and develop an embryo after an egg is fertilized, divide and reproduce, and eventually generate almost all other types of cells in the human body.

On the other hand, the non-embryonic (adult cells) are multipotent – meaning they can only change into some cells, not any cell. They can only do what they have been programmed to do in the body.

However, they are still crucial to the body’s internal repair system all throughout its lifetime. Adult stem cells are rare and are currently only known to be effective when used for the organ in which they are found. While the full effectiveness of these adult cells in the body has still yet to be fully substantiated, different medical studies have led to various breakthroughs for better use of these rare cells.

One very significant achievement was the reprogramming the adult cells to create a special kind of cell known as induced pluripotent cells (iPSCs). iPSCs can be obtained from the basic body layers and reprogrammed into a nascent state.

What is Exosome Stem Cell Therapy?

Essentially, stem cell therapy is the use of stem cells to treat or prevent diseases in the body. Cells are said to be dead when they stop carrying out their functions. This death can occur naturally through a process known as apoptosis, which happens when a particular cell has reached its final stages. Apoptosis is a normal occurrence and also supports the immune system. The other way through which cells die is the process called necrosis. Necrosis is an unplanned cell death due to external factors such as infection, poisoning, or traumatic injury.

Different methods of stem cell treatment have been used in medicine, such as the widely used bone marrow transplant. However, scientists have recently discovered other new methods, including exosome stem cell therapy, which is available to be used by patients who are willing to use the most cutting-edge therapy procedures.

How Does Exosome Stem Cell Therapy Work?

In the past, exosomes were largely ignored in the medical practice. However, over the last three decades, they have been studied far more extensively and have now become one of the most efficient therapies for a variety of medical conditions.

Exosome therapy is a regenerative process whereby tissues with the ability to restore biological functions and structures in the body are being used to reinvigorate nonperforming body cells, which commonly occur due to aging.

Exosomes are derived from certain stem cells—such as mesenchymal and dendritic stem cells—and are very effective in therapeutic treatments. They have been known to be biocompatible and used in combating various kinds of disorders.

How are Exosomes Extracted?

Exosomes are extracellular vesicles that are present in tissue and can also be found in the blood, urine, and cerebrospinal fluid (CSF). The extraction is done by medical experts and usually takes place in a laboratory.

These exosomes can be extracted using different methods such as chromatography, filtration, polymer-based precipitation, immunological separation, and centrifugation. The most common among the methods are the centrifugation techniques.

Regardless of the exact process, the end result is that the cellular components are separated by density, size, and shape. The large vesicles and debris of the stem cells will be removed and discarded, thereby leaving the exosomes. This will be followed by sterile filtration of the exosome solution to create the finished product.

How Is Exosome Stem Cell Therapy Administered?

Exosomes are administered through an intravenous (IV) treatment or an IV push. When used for systemic illnesses that affect the entire body or as an anti-aging treatment, they are given as an IV. As a part of regenerative therapy, however, exosomes are administered intra-articular (i.e., directly into the affected joint area).

The dosage and procedure method are dependent on the individual patient as there is no universal protocol for how it is administered. For some patients, the therapy may be a combination of exosomes with ultrasound, low-level energy, or regional hyperthermia. There is a concentration of 1 billion exosomes in 1 ml of solution, which can be made available in small liquid samples of 1.0mL, 2.0mL, and 5.0mL.

How Many Sessions of Exosome Stem Cell Therapy Will I Need to Undergo

The number of required sessions usually depends on the type and severity of the illness. For some patients, only a single application will be enough, while for others there may be a need for multiple doses. Usually a follow-up is done to monitor the response and help determine if there will be a need for more doses. Therapy may start with a small dose and eventually increase over time.

How Will I Feel After the Exosome Stem Cell Treatment?

Exosome therapy is typically an outpatient treatment, meaning you will be able to walk out of the clinic right after the session without any major pain and will not need to be kept overnight. Although you may experience some level of initial pain or discomfort during the procedure at the injection site, it will likely not be substantial or last very long.

The therapy does not have any significant side effects. In fact, fewer than 10% of exosome administrations report minor cases of headaches, mild fevers, vomiting, or nausea that have been recorded after the therapy. These shouldn’t last for more than two days and usually dissipate within 24 hours. Although you will be able to resume your usual routine immediately after the procedure, it is advisable to stay away from some physical activities for a short time in order to see optimal results.

You will need to avoid strenuous activity for one or two days after the treatment and also refrain from cardio workouts for about three to four weeks. Weight-lifting and running should be avoided for at least four weeks. You will also need to refrain from taking anti-inflammatory medication.


Which Conditions Can Be Treated By Exosome Stem Cell Therapy?

Exosomes belong to the class of extracellular vesicles released by biofluids, such as plasma, urine, and saliva. The vesicles are enriched with ribonucleic acid (RNA), an essential component of biological macromolecules, which carry proteins from the DNA of a cell to its ribosome.

The composition of exosomes makes the therapy very effective in different areas of the body, including psychological and therapeutic processes. Because it is a cell regenerative therapy, exosome therapy is used to treat different neurodegenerative diseases such as Parkinson’s disease, Alzheimer’s disease, Huntington’s disease and amyotrophic lateral sclerosis.

Some other common conditions exosome stem cell therapy can be used for include chronic fatigue, arthritis, wrinkles, muscle weakness and fatigue, as well as chronic autoimmune and inflammatory diseases. It can also be used for chronic kidney problems, coronary artery condition, and heart failure.

Also, inhalation treatment for asthma, COPD, and respiratory issues can be treated using exosomes. Same with wound care cases and peripheral artery disease. The  efficacy of exosome therapy has also been recorded for certain mental disorders.

Usage of Exosome Stem Cell Therapy

Exosomes are used in treating different conditions such as mast cell activation syndrome (MCAS). The RNA inserted into the cells gives instructions needed for the cells to produce their own inflammation regulating substance, thereby stabilizing them and preventing them from becoming dysfunctional.

Exosomes can also be used as a replacement for bone marrow aspirations (BMA) or be used in combination with BMA. Exosomes also play a key role in platelet-rich plasma (PRP) activity as  theyhelps in exploring the therapeutic potentials for cell regeneration. They can also be used with PRP for systemic or IV treatments.

Exosomes can be mixed with PRP for all musculoskeletal (MSK) conditions that need an extra boost and don’t respond to PRP well. They can also be mixed into the IV bag or as a direct push for IV/systemic treatments. Exosomes can also treat other conditions such as: Hair Restoration, Aging Skin, and Sexual Enhancement.

Exosome Stem Cell Therapy for Hair Restoration

With exosomes, using hair implants may soon be a thing of the past. The usage of exosomes will help stimulate your cells to regenerate lost hair. This can be done with or without PRP or protein-concentrating device. There is a lack of strong scientific data on allografts for hair, as PRP by itself doesn’t work well for hair growth. However, the available findings from exosome therapy suggest that the procedure promotes hair growth and regeneration.

Exosome Stem Cell Therapy for Aging Skin

Exosome stem cells can also be used to improve the look and feel of skin, giving you younger-looking skin. This can be done using exosome micro-needling to treat skin problems like stretch marks, wrinkles, pores, lax or thin skin, sun damage, etc. You can use it during PRP facial micro-needling procedures as an upgrade to a standard PRP procedure.

Exosome Stem Cell Therapy for Sexual Enhancement

Exosome therapy is also an effective means of sexual wellness for both men and women. For women, exosome therapy has a regenerative potential that can help reinvigorate your sexual performance if menopause or any age-related conditions have impacted your libido. This is known as an O-shot, a procedure that will cause natural growth factors and reinvigorate your vaginal tissue to create more sexual sensitivity.

For men, this procedure is known as a P-shot, which increases blood flow into the penile area for better and longer erections. Both P-shots and O-shots are very easy procedures with fast results and no down time. You may even resume sexual activity the same day.

How Effective Is Exosome Stem Cell Therapy?

Different medical studies have already established the efficacy of exosome therapy for various conditions. The result will be determined by the severity of the condition and how your body responds to the therapy. When administered, exosomes trigger a two-phase response in the body.

It usually starts with an immediate response which generally lasts for 24 hours or until the initial proteins are broken down. This will be followed by the messenger ribonucleic acid, or RNA, which will help reprogram the cell. Usually 6-10 weeks after the procedure you will be able to experience the benefits of the therapy in your body. The effects may also continue for several months afterward.

How Are Exosomes Stored and Transported?

Exosomes are suspended in saline solution and must be kept frozen. The solution is shipped on dry ice overnight and must be used immediately or kept in a freezer, where it can be kept for up to 6 months. It is not advisable to keep it in a nitrogen tank, or to refreeze it once thawed. The exosome solution does not contain live stem cells and the temperature usually determines its level of concentration.

How Modern Therapy MD Can Help

Exosome stem cell therapy has many benefits that are uncommon in other medical treatments. The easy application, quick procedure, and the lasting results make it a highly favored therapy for both men and women.

We can help you treat the conditions mentioned above, enhance your sexual life, or achieve younger-looking skin with the latest health and age management medical services. At Modern Therapy, we are committed to improving our patients’ quality of life using cutting edge therapies and techniques. You can book an appointment with us today by filling out this free contact form.